COMP protein (Canis lupus familiaris) - STRING interaction network

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Score

COMP

Cartilage oligomeric matrix protein. (891 aa)

Predicted Functional Partners:

MATN3

0.941

ACAN

0.910

DCN

0.847

FMOD

0.833

COL2A1

0.807

MATN4

0.718

BGN

0.695

MMP13

0.680

COL10A1

0.680

CHAD

0.655

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAN	BGN	ENSCAFP00000065577	ENSCAFP00000028297	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.874
ACAN	CHAD	ENSCAFP00000065577	ENSCAFP00000025121	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Chondroadherin.	0.611
ACAN	COL10A1	ENSCAFP00000065577	ENSCAFP00000039411	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Collagen type X alpha 1 chain.	0.828
ACAN	COL2A1	ENSCAFP00000065577	ENSCAFP00000013330	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Collagen type II alpha 1 chain.	0.953
ACAN	COMP	ENSCAFP00000065577	ENSCAFP00000055935	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Cartilage oligomeric matrix protein.	0.910
ACAN	DCN	ENSCAFP00000065577	ENSCAFP00000009230	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.904
ACAN	FMOD	ENSCAFP00000065577	ENSCAFP00000013913	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Fibromodulin.	0.837
ACAN	MATN3	ENSCAFP00000065577	ENSCAFP00000005694	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Matrilin 3.	0.596
ACAN	MMP13	ENSCAFP00000065577	ENSCAFP00000022174	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Matrix metallopeptidase 13.	0.928
BGN	ACAN	ENSCAFP00000028297	ENSCAFP00000065577	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	0.874
BGN	CHAD	ENSCAFP00000028297	ENSCAFP00000025121	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Chondroadherin.	0.509
BGN	COL10A1	ENSCAFP00000028297	ENSCAFP00000039411	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Collagen type X alpha 1 chain.	0.482
BGN	COL2A1	ENSCAFP00000028297	ENSCAFP00000013330	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Collagen type II alpha 1 chain.	0.752
BGN	COMP	ENSCAFP00000028297	ENSCAFP00000055935	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Cartilage oligomeric matrix protein.	0.695
BGN	DCN	ENSCAFP00000028297	ENSCAFP00000009230	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.891
BGN	FMOD	ENSCAFP00000028297	ENSCAFP00000013913	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Fibromodulin.	0.817
BGN	MMP13	ENSCAFP00000028297	ENSCAFP00000022174	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Matrix metallopeptidase 13.	0.491
CHAD	ACAN	ENSCAFP00000025121	ENSCAFP00000065577	Chondroadherin.	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	0.611
CHAD	BGN	ENSCAFP00000025121	ENSCAFP00000028297	Chondroadherin.	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.509
CHAD	COL2A1	ENSCAFP00000025121	ENSCAFP00000013330	Chondroadherin.	Collagen type II alpha 1 chain.	0.489