STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BGLAPOsteocalcin; Belongs to the mitochondrial carrier (TC 2.A.29) family. (473 aa)    
Predicted Functional Partners:
SLC25A51
Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.605
NIPSNAP3B
Nipsnap homolog 3B.
   
  
 0.581
KCNK16-2
Ion_trans_2 domain-containing protein.
   
  
 0.580
TMEM150A
Transmembrane protein 150A.
   
  
 0.579
UBQLN4
Ubiquilin 4.
      
 0.568
TMBIM4
Uncharacterized protein; Belongs to the BI1 family.
   
  
 0.567
MTX1
Metaxin 1.
      
 0.561
IMPDH2
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
    
   0.541
TRIM45
Tripartite motif containing 45.
   
  
 0.523
CDK5RAP3
CDK5 regulatory subunit associated protein 3.
      
 0.523
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.