STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYRO3TYRO3 protein tyrosine kinase. (902 aa)    
Predicted Functional Partners:
GAS6
Growth arrest specific 6.
    
 
 0.736
TULP1
Tubby-like protein; Belongs to the TUB family.
    
 
 0.482
AKT1S1
AKT1 substrate 1.
   
 
 0.481
PROS1
Protein S.
      
 0.470
DIXDC1
DIX domain containing 1.
    
 
 0.463
COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.
   
  
 0.461
CAMTA1
Calmodulin binding transcription activator 1.
      
 0.461
RUBCN
Rubicon autophagy regulator.
    
 
 0.438
SOCS1
Suppressor of cytokine signaling 1.
    
 
 0.438
SMU1
SMU1 DNA replication regulator and spliceosomal factor.
    
 
 0.415
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.