STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFAP1L1Actin filament associated protein 1 like 1. (835 aa)    
Predicted Functional Partners:
VPS53
VPS53 subunit of GARP complex.
      
 0.879
SYT10
Synaptotagmin 10.
      
 0.845
RPH3AL
Rabphilin 3A like (without C2 domains).
   
  
 0.827
GRPEL2
Prenylcysteine oxidase 1 like.
      
 0.809
TDRD5
Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity); Belongs to the TDRD5 family.
      
 0.805
GEMIN4
Gem nuclear organelle associated protein 4.
      
 0.763
CLINT1
Clathrin interactor 1.
   
  
 0.738
ABLIM3
Actin binding LIM protein family member 3.
 
 
  
 0.701
CNTN6
Contactin 6.
      
 0.693
EDA
Ectodysplasin A isoform EDA-A2; Belongs to the tumor necrosis factor family.
      
 0.560
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.