STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAFP00000056794Uncharacterized protein. (226 aa)    
Predicted Functional Partners:
ARID4A
AT-rich interaction domain 4A.
   
 
 0.795
ARID4B
AT-rich interaction domain 4B.
   
 
 0.745
SIN3B
SIN3 transcription regulator family member B.
   
 
 0.736
ING2
Inhibitor of growth protein.
    
 
 0.678
SAP30
Sin3A associated protein 30.
   
 
 0.662
FAM50A
Family with sequence similarity 50 member A.
      
 0.630
PTPN9
SIN3 transcription regulator family member A.
   
 
 0.623
TRIM7
Tripartite motif containing 7.
    
 
 0.577
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 
 0.529
HDAC2
Histone deacetylase 2.
   
 
 0.529
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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