ENSCAFP00000056837 protein (Canis lupus familiaris)

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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[Homology]

Score

ENSCAFP00000056837

Uncharacterized protein. (347 aa)

Predicted Functional Partners:

TMED1

0.559

DOK2

0.554

SPPL3

0.517

SOGA3

0.517

BPIFB1

0.515

ARHGEF2

0.463

FLYWCH1

0.454

MFAP4

0.421

CA6

0.417

CSTA

0.407

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF2	DOK2	ENSCAFP00000057462	ENSCAFP00000014749	Rho guanine nucleotide exchange factor 2; Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras- GTPases. Forms an intracellular sensing system along with NOD1 for the detec [...]	Docking protein 2.	0.493
ARHGEF2	ENSCAFP00000056837	ENSCAFP00000057462	ENSCAFP00000056837	Rho guanine nucleotide exchange factor 2; Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras- GTPases. Forms an intracellular sensing system along with NOD1 for the detec [...]	Uncharacterized protein.	0.463
ARHGEF2	TMED1	ENSCAFP00000057462	ENSCAFP00000026000	Rho guanine nucleotide exchange factor 2; Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras- GTPases. Forms an intracellular sensing system along with NOD1 for the detec [...]	Transmembrane p24 trafficking protein 1.	0.479
BPIFB1	DOK2	ENSCAFP00000051263	ENSCAFP00000014749	BPI fold containing family B member 1.	Docking protein 2.	0.471
BPIFB1	ENSCAFP00000056837	ENSCAFP00000051263	ENSCAFP00000056837	BPI fold containing family B member 1.	Uncharacterized protein.	0.515
BPIFB1	SPPL3	ENSCAFP00000051263	ENSCAFP00000042076	BPI fold containing family B member 1.	Signal peptide peptidase like 3.	0.418
BPIFB1	TMED1	ENSCAFP00000051263	ENSCAFP00000026000	BPI fold containing family B member 1.	Transmembrane p24 trafficking protein 1.	0.514
CA6	ENSCAFP00000056837	ENSCAFP00000029168	ENSCAFP00000056837	Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown (By similarity); Belongs to the alpha-carbonic anhydrase family.	Uncharacterized protein.	0.417
CSTA	ENSCAFP00000056837	ENSCAFP00000017483	ENSCAFP00000056837	Cystatin A; Belongs to the cystatin family.	Uncharacterized protein.	0.407
DOK2	ARHGEF2	ENSCAFP00000014749	ENSCAFP00000057462	Docking protein 2.	Rho guanine nucleotide exchange factor 2; Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras- GTPases. Forms an intracellular sensing system along with NOD1 for the detec [...]	0.493
DOK2	BPIFB1	ENSCAFP00000014749	ENSCAFP00000051263	Docking protein 2.	BPI fold containing family B member 1.	0.471
DOK2	ENSCAFP00000056837	ENSCAFP00000014749	ENSCAFP00000056837	Docking protein 2.	Uncharacterized protein.	0.554
DOK2	MFAP4	ENSCAFP00000014749	ENSCAFP00000047279	Docking protein 2.	Microfibril associated protein 4.	0.500
DOK2	SPPL3	ENSCAFP00000014749	ENSCAFP00000042076	Docking protein 2.	Signal peptide peptidase like 3.	0.527
DOK2	TMED1	ENSCAFP00000014749	ENSCAFP00000026000	Docking protein 2.	Transmembrane p24 trafficking protein 1.	0.657
ENSCAFP00000056837	ARHGEF2	ENSCAFP00000056837	ENSCAFP00000057462	Uncharacterized protein.	Rho guanine nucleotide exchange factor 2; Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras- GTPases. Forms an intracellular sensing system along with NOD1 for the detec [...]	0.463
ENSCAFP00000056837	BPIFB1	ENSCAFP00000056837	ENSCAFP00000051263	Uncharacterized protein.	BPI fold containing family B member 1.	0.515
ENSCAFP00000056837	CA6	ENSCAFP00000056837	ENSCAFP00000029168	Uncharacterized protein.	Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown (By similarity); Belongs to the alpha-carbonic anhydrase family.	0.417
ENSCAFP00000056837	CSTA	ENSCAFP00000056837	ENSCAFP00000017483	Uncharacterized protein.	Cystatin A; Belongs to the cystatin family.	0.407
ENSCAFP00000056837	DOK2	ENSCAFP00000056837	ENSCAFP00000014749	Uncharacterized protein.	Docking protein 2.	0.554