AAGAB protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AAGAB

Alpha and gamma adaptin binding protein. (381 aa)

Predicted Functional Partners:

MFSD9

0.785

PGAP3

0.785

AP2S1

0.731

EXOC5

0.713

TGFBRAP1

0.683

ELFN2

0.681

PTPN23

0.679

CCDC115

0.676

RABGEF1

0.646

SLC35A1

0.646

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAGAB	AP2S1	ENSCAFP00000057161	ENSCAFP00000057273	Alpha and gamma adaptin binding protein.	Adaptor related protein complex 2 subunit sigma 1.	0.731
AAGAB	CCDC115	ENSCAFP00000057161	ENSCAFP00000036040	Alpha and gamma adaptin binding protein.	Coiled-coil domain containing 115.	0.676
AAGAB	ELFN2	ENSCAFP00000057161	ENSCAFP00000044405	Alpha and gamma adaptin binding protein.	Extracellular leucine rich repeat and fibronectin type III domain containing 2.	0.681
AAGAB	EXOC5	ENSCAFP00000057161	ENSCAFP00000022452	Alpha and gamma adaptin binding protein.	Exocyst complex component 5.	0.713
AAGAB	MFSD9	ENSCAFP00000057161	ENSCAFP00000031744	Alpha and gamma adaptin binding protein.	Major facilitator superfamily domain containing 9.	0.785
AAGAB	PGAP3	ENSCAFP00000057161	ENSCAFP00000051939	Alpha and gamma adaptin binding protein.	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	0.785
AAGAB	PTPN23	ENSCAFP00000057161	ENSCAFP00000042483	Alpha and gamma adaptin binding protein.	Protein tyrosine phosphatase non-receptor type 23.	0.679
AAGAB	RABGEF1	ENSCAFP00000057161	ENSCAFP00000015865	Alpha and gamma adaptin binding protein.	RAB guanine nucleotide exchange factor 1.	0.646
AAGAB	SLC35A1	ENSCAFP00000057161	ENSCAFP00000052549	Alpha and gamma adaptin binding protein.	Solute carrier family 35 member A1.	0.646
AAGAB	TGFBRAP1	ENSCAFP00000057161	ENSCAFP00000003101	Alpha and gamma adaptin binding protein.	Transforming growth factor beta receptor associated protein 1.	0.683
AP2S1	AAGAB	ENSCAFP00000057273	ENSCAFP00000057161	Adaptor related protein complex 2 subunit sigma 1.	Alpha and gamma adaptin binding protein.	0.731
CCDC115	AAGAB	ENSCAFP00000036040	ENSCAFP00000057161	Coiled-coil domain containing 115.	Alpha and gamma adaptin binding protein.	0.676
CCDC115	SLC35A1	ENSCAFP00000036040	ENSCAFP00000052549	Coiled-coil domain containing 115.	Solute carrier family 35 member A1.	0.705
ELFN2	AAGAB	ENSCAFP00000044405	ENSCAFP00000057161	Extracellular leucine rich repeat and fibronectin type III domain containing 2.	Alpha and gamma adaptin binding protein.	0.681
ELFN2	MFSD9	ENSCAFP00000044405	ENSCAFP00000031744	Extracellular leucine rich repeat and fibronectin type III domain containing 2.	Major facilitator superfamily domain containing 9.	0.677
ELFN2	PGAP3	ENSCAFP00000044405	ENSCAFP00000051939	Extracellular leucine rich repeat and fibronectin type III domain containing 2.	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	0.677
EXOC5	AAGAB	ENSCAFP00000022452	ENSCAFP00000057161	Exocyst complex component 5.	Alpha and gamma adaptin binding protein.	0.713
EXOC5	PTPN23	ENSCAFP00000022452	ENSCAFP00000042483	Exocyst complex component 5.	Protein tyrosine phosphatase non-receptor type 23.	0.637
EXOC5	RABGEF1	ENSCAFP00000022452	ENSCAFP00000015865	Exocyst complex component 5.	RAB guanine nucleotide exchange factor 1.	0.626
EXOC5	SLC35A1	ENSCAFP00000022452	ENSCAFP00000052549	Exocyst complex component 5.	Solute carrier family 35 member A1.	0.566