STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHRNECholinergic receptor nicotinic epsilon subunit. (662 aa)    
Predicted Functional Partners:
RAPSN
Receptor associated protein of the synapse.
   
 
 0.765
ALG14
ALG14 UDP-N-acetylglucosaminyltransferase subunit.
   
  
 0.707
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
  
 
0.681
CHRNA4
Cholinergic receptor nicotinic alpha 4 subunit.
  
 
0.660
DOK7
Docking protein 7.
   
  
 0.659
GFPT1
Glutamine--fructose-6-phosphate transaminase 1.
      
 0.640
MUSK
Muscle associated receptor tyrosine kinase.
   
 
 0.616
SLC5A7
Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.612
SCN4A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
  
 0.598
DPAGT1
Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1.
      
 0.594
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.