ENSCAFP00000057814 protein (Canis lupus familiaris)

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

ENSCAFP00000057814

Uncharacterized protein. (151 aa)

Predicted Functional Partners:

ITSN2

0.833

LOC100856635

0.763

ITSN1

0.763

ROCK1

0.584

ARHGAP35

0.573

PKN1

0.568

ARHGEF28

0.549

ARHGEF12

0.533

ARHGEF18

0.528

ARHGEF11

0.528

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP35	ENSCAFP00000057814	ENSCAFP00000036971	ENSCAFP00000057814	Rho GTPase-activating protein 35; Rho GTPase-activating protein (GAP). Binds several acidic phospholipids which inhibits the Rho GAP activity to promote the Rac GAP activity. This binding is inhibited by phosphorylation by PRKCA (By similarity). Involved in cell differentiation as well as cell adhesion and migration, plays an important role in retinal tissue morphogenesis, neural tube fusion, midline fusion of the cerebral hemispheres and mammary gland branching morphogenesis (By similarity). Transduces signals from p21-ras to the nucleus, acting via the ras GTPase- activating protein [...]	Uncharacterized protein.	0.573
ARHGEF11	ARHGEF12	ENSCAFP00000054172	ENSCAFP00000017590	Rho guanine nucleotide exchange factor 11.	Rho guanine nucleotide exchange factor 12.	0.926
ARHGEF11	ENSCAFP00000057814	ENSCAFP00000054172	ENSCAFP00000057814	Rho guanine nucleotide exchange factor 11.	Uncharacterized protein.	0.528
ARHGEF11	ROCK1	ENSCAFP00000054172	ENSCAFP00000050426	Rho guanine nucleotide exchange factor 11.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.663
ARHGEF12	ARHGEF11	ENSCAFP00000017590	ENSCAFP00000054172	Rho guanine nucleotide exchange factor 12.	Rho guanine nucleotide exchange factor 11.	0.926
ARHGEF12	ARHGEF28	ENSCAFP00000017590	ENSCAFP00000066525	Rho guanine nucleotide exchange factor 12.	Rho guanine nucleotide exchange factor 28.	0.912
ARHGEF12	ENSCAFP00000057814	ENSCAFP00000017590	ENSCAFP00000057814	Rho guanine nucleotide exchange factor 12.	Uncharacterized protein.	0.533
ARHGEF12	ROCK1	ENSCAFP00000017590	ENSCAFP00000050426	Rho guanine nucleotide exchange factor 12.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.618
ARHGEF18	ENSCAFP00000057814	ENSCAFP00000026917	ENSCAFP00000057814	Uncharacterized protein.	Uncharacterized protein.	0.528
ARHGEF28	ARHGEF12	ENSCAFP00000066525	ENSCAFP00000017590	Rho guanine nucleotide exchange factor 28.	Rho guanine nucleotide exchange factor 12.	0.912
ARHGEF28	ENSCAFP00000057814	ENSCAFP00000066525	ENSCAFP00000057814	Rho guanine nucleotide exchange factor 28.	Uncharacterized protein.	0.549
ARHGEF28	ROCK1	ENSCAFP00000066525	ENSCAFP00000050426	Rho guanine nucleotide exchange factor 28.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.555
ENSCAFP00000057814	ARHGAP35	ENSCAFP00000057814	ENSCAFP00000036971	Uncharacterized protein.	Rho GTPase-activating protein 35; Rho GTPase-activating protein (GAP). Binds several acidic phospholipids which inhibits the Rho GAP activity to promote the Rac GAP activity. This binding is inhibited by phosphorylation by PRKCA (By similarity). Involved in cell differentiation as well as cell adhesion and migration, plays an important role in retinal tissue morphogenesis, neural tube fusion, midline fusion of the cerebral hemispheres and mammary gland branching morphogenesis (By similarity). Transduces signals from p21-ras to the nucleus, acting via the ras GTPase- activating protein [...]	0.573
ENSCAFP00000057814	ARHGEF11	ENSCAFP00000057814	ENSCAFP00000054172	Uncharacterized protein.	Rho guanine nucleotide exchange factor 11.	0.528
ENSCAFP00000057814	ARHGEF12	ENSCAFP00000057814	ENSCAFP00000017590	Uncharacterized protein.	Rho guanine nucleotide exchange factor 12.	0.533
ENSCAFP00000057814	ARHGEF18	ENSCAFP00000057814	ENSCAFP00000026917	Uncharacterized protein.	Uncharacterized protein.	0.528
ENSCAFP00000057814	ARHGEF28	ENSCAFP00000057814	ENSCAFP00000066525	Uncharacterized protein.	Rho guanine nucleotide exchange factor 28.	0.549
ENSCAFP00000057814	ITSN1	ENSCAFP00000057814	ENSCAFP00000062904	Uncharacterized protein.	Intersectin 1.	0.763
ENSCAFP00000057814	ITSN2	ENSCAFP00000057814	ENSCAFP00000006002	Uncharacterized protein.	Intersectin 2.	0.833
ENSCAFP00000057814	LOC100856635	ENSCAFP00000057814	ENSCAFP00000014017	Uncharacterized protein.	Uncharacterized protein.	0.763