STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HHATHedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family. (591 aa)    
Predicted Functional Partners:
DHH
Desert hedgehog signaling molecule.
   
 0.913
AASDH
Aminoadipate-semialdehyde dehydrogenase.
  
  
 0.899
NDUFAB1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.858
PALB2
Partner and localizer of BRCA2.
  
 
 0.858
J9P1J9_CANLF
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.858
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.858
DMRT2
Doublesex and mab-3 related transcription factor 2.
   
  
 0.744
WWOX
WW domain containing oxidoreductase.
     
 0.643
ENTPD4
Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family.
      
 0.639
SOX3
SRY-box 3.
    
 
 0.579
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.