STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC4A4Anion exchange protein. (1096 aa)    
Predicted Functional Partners:
SLC26A6
Solute carrier family 26 member 6.
      
 0.583
CA2
Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family.
   
 
 0.581
CCDC82
Coiled-coil domain containing 82.
      
 0.568
OR5R1
Olfactory receptor.
      
 0.566
GPALPP1
GPALPP motifs containing 1.
      
 0.565
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]
   
 
 0.539
SLC9A1
Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
    
 
 0.536
ZNF831
Zinc finger protein 831.
   
  
 0.529
UBTF
Upstream binding transcription factor.
      
 0.527
SLC5A12
Solute carrier family 5 member 12; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.521
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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