STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBEAL2Neurobeachin like 2. (2687 aa)    
Predicted Functional Partners:
RABGGTA
Rab geranylgeranyltransferase subunit alpha.
   
  
 0.875
VIPAS39
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog.
      
 0.783
TMEM51
Transmembrane protein 51.
   
  
 0.769
CDC42EP3
CDC42 effector protein 3.
   
  
 0.681
MYH9
Myosin-9; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10 (By similarity). Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.649
UBE2K
Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.
      
 0.617
VPS33B
VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family.
   
  
 0.578
CCDC12
Coiled-coil domain containing 12.
      
 0.558
METTL9
Methyltransferase like 9.
      
 0.529
MOXD1
Monooxygenase DBH like 1.
      
 0.516
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.