STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JMJD8Jumonji domain containing 8. (291 aa)    
Predicted Functional Partners:
SNF8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
 
      0.684
WDR24
WD repeat domain 24.
 
 
  
 0.605
JMJD4
Jumonji domain containing 4.
   
  
 0.539
PEF1
Penta-EF-hand domain containing 1.
   
  
 0.538
IFFO1
Intermediate filament family orphan 1; Belongs to the intermediate filament family.
   
  
 0.510
IFFO2
Intermediate filament family orphan 2; Belongs to the intermediate filament family.
      
 0.508
EFCC1
EF-hand and coiled-coil domain containing 1.
      
 0.482
TET3
Tet methylcytosine dioxygenase 3.
      
 0.482
EVX2
Even-skipped homeobox 2.
      
 0.480
CD302
Uncharacterized protein.
    
 
 0.401
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.