MEGF10 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

MEGF10

Multiple EGF like domains 10. (1147 aa)

Predicted Functional Partners:

MTREX

0.646

GULP1

0.639

CRAMP1

0.607

JPT2

0.607

SGCG

0.599

ACTN3

0.576

MERTK

0.534

MEGF8

0.531

CCDC78

0.517

GAS6

0.515

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN3	MEGF10	ENSCAFP00000018519	ENSCAFP00000058220	Actinin alpha 3.	Multiple EGF like domains 10.	0.576
ACTN3	SGCG	ENSCAFP00000018519	ENSCAFP00000010630	Actinin alpha 3.	Gamma-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.	0.585
CCDC78	MEGF10	ENSCAFP00000051587	ENSCAFP00000058220	Coiled-coil domain containing 78.	Multiple EGF like domains 10.	0.517
CRAMP1	JPT2	ENSCAFP00000021068	ENSCAFP00000046278	Cramped chromatin regulator homolog 1.	Jupiter microtubule associated homolog 2.	0.829
CRAMP1	MEGF10	ENSCAFP00000021068	ENSCAFP00000058220	Cramped chromatin regulator homolog 1.	Multiple EGF like domains 10.	0.607
CRAMP1	MTREX	ENSCAFP00000021068	ENSCAFP00000010181	Cramped chromatin regulator homolog 1.	Mtr4 exosome RNA helicase.	0.824
GAS6	MEGF10	ENSCAFP00000048221	ENSCAFP00000058220	Growth arrest specific 6.	Multiple EGF like domains 10.	0.515
GAS6	MERTK	ENSCAFP00000048221	ENSCAFP00000039976	Growth arrest specific 6.	MER proto-oncogene, tyrosine kinase.	0.967
GULP1	MEGF10	ENSCAFP00000060781	ENSCAFP00000058220	GULP PTB domain containing engulfment adaptor 1.	Multiple EGF like domains 10.	0.639
JPT2	CRAMP1	ENSCAFP00000046278	ENSCAFP00000021068	Jupiter microtubule associated homolog 2.	Cramped chromatin regulator homolog 1.	0.829
JPT2	MEGF10	ENSCAFP00000046278	ENSCAFP00000058220	Jupiter microtubule associated homolog 2.	Multiple EGF like domains 10.	0.607
JPT2	MTREX	ENSCAFP00000046278	ENSCAFP00000010181	Jupiter microtubule associated homolog 2.	Mtr4 exosome RNA helicase.	0.833
MEGF10	ACTN3	ENSCAFP00000058220	ENSCAFP00000018519	Multiple EGF like domains 10.	Actinin alpha 3.	0.576
MEGF10	CCDC78	ENSCAFP00000058220	ENSCAFP00000051587	Multiple EGF like domains 10.	Coiled-coil domain containing 78.	0.517
MEGF10	CRAMP1	ENSCAFP00000058220	ENSCAFP00000021068	Multiple EGF like domains 10.	Cramped chromatin regulator homolog 1.	0.607
MEGF10	GAS6	ENSCAFP00000058220	ENSCAFP00000048221	Multiple EGF like domains 10.	Growth arrest specific 6.	0.515
MEGF10	GULP1	ENSCAFP00000058220	ENSCAFP00000060781	Multiple EGF like domains 10.	GULP PTB domain containing engulfment adaptor 1.	0.639
MEGF10	JPT2	ENSCAFP00000058220	ENSCAFP00000046278	Multiple EGF like domains 10.	Jupiter microtubule associated homolog 2.	0.607
MEGF10	MEGF8	ENSCAFP00000058220	ENSCAFP00000007208	Multiple EGF like domains 10.	Multiple EGF like domains 8.	0.531
MEGF10	MERTK	ENSCAFP00000058220	ENSCAFP00000039976	Multiple EGF like domains 10.	MER proto-oncogene, tyrosine kinase.	0.534