STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACP3Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. (436 aa)    
Predicted Functional Partners:
KLK2
Arginine esterase; This serine protease is found in dog seminal plasma, its exact physiological function is not known.
   
 
 0.629
ELK4
ETS transcription factor ELK4.
      
 0.606
PPP1R37
Protein phosphatase 1 regulatory subunit 37.
   
  
 0.569
ANOS1
Anosmin 1.
      
 0.566
MKI67
Marker of proliferation Ki-67.
      
 0.561
TMPRSS2
Uncharacterized protein.
    
 
 0.558
UPK3B
Uroplakin 3B.
      
 0.528
PSCA
Prostate stem cell antigen.
    
 
 0.523
KCNJ1
Potassium voltage-gated channel subfamily J member 1.
      
 0.515
PLBD2
Phospholipase B-like; Putative phospholipase.
      
 0.514
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.