STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC25A1Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (359 aa)    
Predicted Functional Partners:
CS
Citrate synthase; Belongs to the citrate synthase family.
   
 
 0.929
ACLY
ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.
   
 
 0.767
POLE2
DNA polymerase epsilon 2, accessory subunit.
   
   0.738
GRN
Granulin precursor.
   
   0.726
PCYT2
Phosphate cytidylyltransferase 2, ethanolamine.
   
  
 0.720
CXHXorf56
Chromosome X CXorf56 homolog.
    
   0.719
SLC25A53
Solute carrier family 25 member 53; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.707
SLC33A1
Solute carrier family 33 member 1.
   
  
 0.642
SLC25A6
Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
 
0.637
SLC25A5
Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
 
0.637
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.