STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POF1BPOF1B actin binding protein. (598 aa)    
Predicted Functional Partners:
ZNF711
Zinc finger protein 711.
      
 0.880
PCED1A
PC-esterase domain containing 1A.
      
 0.808
RNF24
Ring finger protein 24.
      
 0.792
VPS16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
      
 0.788
DIAPH2
Diaphanous related formin 2.
   
  
 0.763
PTPRA
Receptor-type tyrosine-protein phosphatase alpha.
      
 0.740
PSMA8
Proteasome subunit alpha type.
   
  
 0.675
LOC612847
Dachshund family transcription factor 2.
   
  
 0.646
PANK2
Pantothenate kinase 2.
      
 0.566
J9P2Z7_CANLF
Uncharacterized protein.
      
 0.564
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.