STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CERKLCeramide kinase like. (870 aa)    
Predicted Functional Partners:
VWA3A
Von Willebrand factor A domain containing 3A.
   
    0.816
ENO4
Enolase 4.
   
  
 0.816
VWA3B
Von Willebrand factor A domain containing 3B.
   
    0.806
DNAH10
Dynein axonemal heavy chain 10.
   
    0.805
RLBP1
Retinaldehyde binding protein 1.
   
 
 0.789
RGR
Retinal G protein coupled receptor; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
   
  
 0.720
CDHR1
Cadherin related family member 1.
   
  
 0.713
CNGA1
cGMP-gated cation channel alpha-1; Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.
   
  
 0.707
TULP1
Tubby-like protein; Belongs to the TUB family.
   
 
 0.701
USH2A
Usherin.
   
 
 0.691
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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