STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP20Rho GTPase activating protein 20. (1266 aa)    
Predicted Functional Partners:
GTF2E2
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
      
 0.877
RIOK1
Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
      
 0.822
MAP3K9
Mitogen-activated protein kinase kinase kinase.
   
  
 0.821
NUDT7
Nudix hydrolase 7.
   
    0.805
PIWIL2
Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.
      
 0.800
CCAR1
Cell division cycle and apoptosis regulator 1.
   
  
 0.732
TBL2
Transducin beta like 2.
      
 0.618
ASB1
Ankyrin repeat and SOCS box containing 1.
      
 0.612
ASB3
Uncharacterized protein.
   
  
 0.606
DDX50
DExD-box helicase 50.
   
  
 0.578
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.