STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRAT1Uncharacterized protein. (249 aa)    
Predicted Functional Partners:
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
 0.993
AXIN1
Axin 1.
    
 0.718
GSK3A
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.606
EBP
Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family.
      
 0.515
MAP3K4
Mitogen-activated protein kinase kinase kinase 4.
      
 0.499
DACT1
Dishevelled binding antagonist of beta catenin 1.
      
 0.487
GYS1
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
      
 0.472
SGK3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
      
 0.472
PPP2CB
Serine/threonine-protein phosphatase.
     
 0.457
PPP2CA
Serine/threonine-protein phosphatase.
     
 0.457
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.