STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HGDHomogentisate 1,2-dioxygenase. (462 aa)    
Predicted Functional Partners:
GSTZ1
Glutathione S-transferase zeta 1; Belongs to the GST superfamily.
 
 
 0.994
HPDL
4-hydroxyphenylpyruvate dioxygenase.
 
 0.983
HPD
4-hydroxyphenylpyruvate dioxygenase; Belongs to the 4HPPD family.
  
 0.980
FAH
Fumarylacetoacetase.
 
 0.945
PAH
Phenylalanine hydroxylase.
  
  
 0.837
F13B
Coagulation factor XIII B chain.
   
  
 0.818
KCNIP3
Potassium voltage-gated channel interacting protein 3.
  
 
 0.810
FAHD1
Fumarylacetoacetate hydrolase domain containing 1.
  
 
 0.808
TAT
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
  
 0.794
AASS
Aminoadipate-semialdehyde synthase.
   
  
 0.793
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.