STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDFY3WD repeat and FYVE domain containing 3. (3630 aa)    
Predicted Functional Partners:
SNX8
Sorting nexin 8.
    
 
 0.816
DACT3
Dishevelled binding antagonist of beta catenin 3.
      
 0.809
GABARAPL1
GABA type A receptor associated protein like 1.
   
 
 0.717
SQSTM1
Sequestosome 1.
   
 
 0.692
GABARAP
GABA type A receptor-associated protein.
   
 
 0.691
ATG5
Autophagy protein 5; Involved in autophagic vesicle formation.
    
 
 0.685
TBC1D19
TBC1 domain family member 19.
   
  
 0.672
WDFY2
WD repeat and FYVE domain containing 2.
   
  
0.654
NBR1
NBR1 autophagy cargo receptor.
   
 
 0.639
LRRC18
Leucine rich repeat containing 18.
      
 0.610
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.