node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CSF1 | CSF1R | ENSCAFP00000059552 | ENSCAFP00000053521 | Colony stimulating factor 1. | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.999 |
CSF1 | CSF2 | ENSCAFP00000059552 | ENSCAFP00000032076 | Colony stimulating factor 1. | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | 0.811 |
CSF1 | EGFR | ENSCAFP00000059552 | ENSCAFP00000005164 | Colony stimulating factor 1. | Receptor protein-tyrosine kinase. | 0.883 |
CSF1 | FLT1 | ENSCAFP00000059552 | ENSCAFP00000010012 | Colony stimulating factor 1. | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.787 |
CSF1 | FLT3 | ENSCAFP00000059552 | ENSCAFP00000051387 | Colony stimulating factor 1. | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.842 |
CSF1 | IL34 | ENSCAFP00000059552 | ENSCAFP00000056375 | Colony stimulating factor 1. | Interleukin 34. | 0.980 |
CSF1 | KDR | ENSCAFP00000059552 | ENSCAFP00000003064 | Colony stimulating factor 1. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.793 |
CSF1 | KIT | ENSCAFP00000059552 | ENSCAFP00000003042 | Colony stimulating factor 1. | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] | 0.930 |
CSF1 | PDGFRA | ENSCAFP00000059552 | ENSCAFP00000065738 | Colony stimulating factor 1. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.841 |
CSF1 | PDGFRB | ENSCAFP00000059552 | ENSCAFP00000000714 | Colony stimulating factor 1. | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at v [...] | 0.830 |
CSF1R | CSF1 | ENSCAFP00000053521 | ENSCAFP00000059552 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Colony stimulating factor 1. | 0.999 |
CSF1R | CSF2 | ENSCAFP00000053521 | ENSCAFP00000032076 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | 0.539 |
CSF1R | EGFR | ENSCAFP00000053521 | ENSCAFP00000005164 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Receptor protein-tyrosine kinase. | 0.540 |
CSF1R | IL34 | ENSCAFP00000053521 | ENSCAFP00000056375 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Interleukin 34. | 0.999 |
CSF2 | CSF1 | ENSCAFP00000032076 | ENSCAFP00000059552 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Colony stimulating factor 1. | 0.811 |
CSF2 | CSF1R | ENSCAFP00000032076 | ENSCAFP00000053521 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.539 |
CSF2 | EGFR | ENSCAFP00000032076 | ENSCAFP00000005164 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Receptor protein-tyrosine kinase. | 0.789 |
CSF2 | FLT3 | ENSCAFP00000032076 | ENSCAFP00000051387 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.631 |
CSF2 | IL34 | ENSCAFP00000032076 | ENSCAFP00000056375 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Interleukin 34. | 0.484 |
CSF2 | PDGFRA | ENSCAFP00000032076 | ENSCAFP00000065738 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.760 |