STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCC2GRIP and coiled-coil domain containing 2. (1752 aa)    
Predicted Functional Partners:
RAB9A
Ras-related protein Rab-9A; Involved in the transport of proteins between the endosomes and the trans-Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity). Belongs to the small GTPase superfamily. Rab family.
   
 
 0.919
RAB9B
RAB9B, member RAS oncogene family.
     
 0.919
GCC1
GRIP and coiled-coil domain containing 1.
   
 
 0.918
STX10
Syntaxin 10; Belongs to the syntaxin family.
   
 
 0.917
RAB6A
RAB6A, member RAS oncogene family.
   
 0.852
RAB6B
RAB6B, member RAS oncogene family.
    
 0.851
GORASP1
Golgi reassembly stacking protein 1.
   
  
 0.846
SCUBE1
Signal peptide, CUB domain and EGF like domain containing 1.
    
 
 0.812
NUP93
Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family.
   
 
 0.767
NUP54
Nucleoporin 54.
   
 
 0.765
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.