STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLK4CDC like kinase 4; Belongs to the protein kinase superfamily. (494 aa)    
Predicted Functional Partners:
CLK1
CDC like kinase 1.
  
 
 
0.982
PRPF18
SFM domain-containing protein.
   
  
 0.779
RSRC1
Arginine and serine rich coiled-coil 1.
      
 0.741
THRAP3
Thyroid hormone receptor associated protein 3.
   
 
 0.721
SRSF1
Serine and arginine rich splicing factor 1.
   
 
 0.668
CWC22
CWC22 spliceosome associated protein homolog.
   
  
 0.657
IRX1
Iroquois homeobox 1.
   
  
 0.655
RNPS1
RNA binding protein with serine rich domain 1.
   
 
 0.654
PIK3C2G
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family.
      
 0.652
ANHX
Anomalous homeobox.
      
 0.574
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.