STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TACC2Transforming acidic coiled-coil containing protein 2. (2955 aa)    
Predicted Functional Partners:
PDILT
Protein disulfide isomerase like, testis expressed.
   
 
 0.822
TDRD6
Tudor domain containing 6.
      
 0.808
CKAP5
Cytoskeleton associated protein 5.
   
 
 0.808
PURA
Purine rich element binding protein A.
   
  
 0.755
TACC1
Transforming acidic coiled-coil containing protein 1.
   
 
0.701
DLGAP2
DLG associated protein 2.
   
  
 0.680
FAM83G
Family with sequence similarity 83 member G.
      
 0.677
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
   
 
 0.677
USP4
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
  
 0.651
KLHL14
Kelch like family member 14.
    
 
 0.643
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.