STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)    
Predicted Functional Partners:
PLXNA2
Plexin A2.
    
 
0.845
CHCHD6
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
    
 
 0.840
PLXNA4
Plexin A4.
    
 
0.813
PLXNA3
Plexin A3.
    
 
 0.773
SIPA1L1
Signal induced proliferation associated 1 like 1.
   
  
 0.712
TCTN1
Tectonic family member 1.
      
 0.642
NRP1
Neuropilin 1.
    
 
 0.627
RASL11B
RAS like family 11 member B.
   
 
 0.607
LRRC2
Leucine rich repeat containing 2.
      
 0.568
EVL
Enah/Vasp-like.
    
 
 0.535
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.