STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (406 aa)    
Predicted Functional Partners:
TUBGCP3
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
      
 0.674
EZR
FERM domain-containing protein.
   
 
 0.618
CLIC4
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
  
 
0.596
KATNAL1
Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...]
      
 0.575
MID1IP1
MID1 interacting protein 1.
   
  
 0.573
TACC1
Transforming acidic coiled-coil containing protein 1.
      
 0.571
STRBP
Spermatid perinuclear RNA binding protein.
      
 0.569
KIFAP3
Kinesin associated protein 3.
      
 0.561
CLIC2
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
  
 
0.544
RDX
Radixin.
   
 
 0.532
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.