DOCK8 protein (Canis lupus familiaris) - STRING interaction network

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Score

DOCK8

Dedicator of cytokinesis 8; Belongs to the DOCK family. (2093 aa)

Predicted Functional Partners:

CDC42

0.868

LRCH1

0.787

CDC42-2

0.785

LRCH3

0.755

J9NYK5_CANLF

0.748

J9P730_CANLF

0.748

DOCK2

0.746

HNRNPR

0.739

ARID4B

0.734

GGNBP2

0.719

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID4B	DOCK8	ENSCAFP00000016861	ENSCAFP00000060841	AT-rich interaction domain 4B.	Dedicator of cytokinesis 8; Belongs to the DOCK family.	0.734
ARID4B	GGNBP2	ENSCAFP00000016861	ENSCAFP00000041487	AT-rich interaction domain 4B.	Gametogenetin binding protein 2.	0.846
ARID4B	HNRNPR	ENSCAFP00000016861	ENSCAFP00000019636	AT-rich interaction domain 4B.	Heterogeneous nuclear ribonucleoprotein R.	0.726
CDC42	DOCK2	ENSCAFP00000021684	ENSCAFP00000024998	Cell division cycle 42.	Dedicator of cytokinesis 2; Belongs to the DOCK family.	0.716
CDC42	DOCK8	ENSCAFP00000021684	ENSCAFP00000060841	Cell division cycle 42.	Dedicator of cytokinesis 8; Belongs to the DOCK family.	0.868
CDC42-2	DOCK2	ENSCAFP00000060180	ENSCAFP00000024998	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Dedicator of cytokinesis 2; Belongs to the DOCK family.	0.546
CDC42-2	DOCK8	ENSCAFP00000060180	ENSCAFP00000060841	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Dedicator of cytokinesis 8; Belongs to the DOCK family.	0.785
DOCK2	CDC42	ENSCAFP00000024998	ENSCAFP00000021684	Dedicator of cytokinesis 2; Belongs to the DOCK family.	Cell division cycle 42.	0.716
DOCK2	CDC42-2	ENSCAFP00000024998	ENSCAFP00000060180	Dedicator of cytokinesis 2; Belongs to the DOCK family.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.546
DOCK2	DOCK8	ENSCAFP00000024998	ENSCAFP00000060841	Dedicator of cytokinesis 2; Belongs to the DOCK family.	Dedicator of cytokinesis 8; Belongs to the DOCK family.	0.746
DOCK2	J9NYK5_CANLF	ENSCAFP00000024998	ENSCAFP00000038374	Dedicator of cytokinesis 2; Belongs to the DOCK family.	Uncharacterized protein.	0.419
DOCK2	J9P730_CANLF	ENSCAFP00000024998	ENSCAFP00000041464	Dedicator of cytokinesis 2; Belongs to the DOCK family.	Uncharacterized protein.	0.419
DOCK8	ARID4B	ENSCAFP00000060841	ENSCAFP00000016861	Dedicator of cytokinesis 8; Belongs to the DOCK family.	AT-rich interaction domain 4B.	0.734
DOCK8	CDC42	ENSCAFP00000060841	ENSCAFP00000021684	Dedicator of cytokinesis 8; Belongs to the DOCK family.	Cell division cycle 42.	0.868
DOCK8	CDC42-2	ENSCAFP00000060841	ENSCAFP00000060180	Dedicator of cytokinesis 8; Belongs to the DOCK family.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.785
DOCK8	DOCK2	ENSCAFP00000060841	ENSCAFP00000024998	Dedicator of cytokinesis 8; Belongs to the DOCK family.	Dedicator of cytokinesis 2; Belongs to the DOCK family.	0.746
DOCK8	GGNBP2	ENSCAFP00000060841	ENSCAFP00000041487	Dedicator of cytokinesis 8; Belongs to the DOCK family.	Gametogenetin binding protein 2.	0.719
DOCK8	HNRNPR	ENSCAFP00000060841	ENSCAFP00000019636	Dedicator of cytokinesis 8; Belongs to the DOCK family.	Heterogeneous nuclear ribonucleoprotein R.	0.739
DOCK8	J9NYK5_CANLF	ENSCAFP00000060841	ENSCAFP00000038374	Dedicator of cytokinesis 8; Belongs to the DOCK family.	Uncharacterized protein.	0.748
DOCK8	J9P730_CANLF	ENSCAFP00000060841	ENSCAFP00000041464	Dedicator of cytokinesis 8; Belongs to the DOCK family.	Uncharacterized protein.	0.748