STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FUBP1Uncharacterized protein. (707 aa)    
Predicted Functional Partners:
PUF60
Poly(U) binding splicing factor 60.
   
 
 0.955
HNRNPA2B1
Heterogeneous nuclear ribonucleoprotein A2/B1.
   
 
 0.781
KHSRP
KH-type splicing regulatory protein.
  
  
0.636
SFPQ
Splicing factor proline and glutamine rich.
   
 
 0.625
ELAVL1
ELAV-like protein; Belongs to the RRM elav family.
   
 
 0.622
SRSF11
Serine and arginine rich splicing factor 11.
   
  
 0.610
NOP58
NOP58 ribonucleoprotein.
   
  
 0.609
SRSF3
Serine and arginine rich splicing factor 3.
   
 
 0.604
QKI
Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).
   
 
 0.603
PRPF40A
Pre-mRNA processing factor 40 homolog A.
   
 
 0.603
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.