STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RGS11Regulator of G protein signaling 11. (471 aa)    
Predicted Functional Partners:
TRPM1
Transient receptor potential cation channel subfamily M member 1.
      
 0.991
GPR158
G protein-coupled receptor 158.
   
 
 0.955
GNB5
G protein subunit beta 5.
   
 0.952
LRIT3
Leucine rich repeat, Ig-like and transmembrane domains 3.
   
  
 0.903
RGS7BP
Regulator of G protein signaling 7 binding protein.
   
 
 0.882
RGS7
Regulator of G protein signaling 7.
  
 
0.869
RGS9BP
Regulator of G protein signaling 9 binding protein.
   
 
 0.852
GNB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 
 0.825
ATE1
Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Belongs to the R-transferase family.
    
 
 0.781
GNAT3
G protein subunit alpha transducin 3.
   
 0.766
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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