STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP21Rho GTPase activating protein 21. (1940 aa)    
Predicted Functional Partners:
RPRD1B
Regulation of nuclear pre-mRNA domain containing 1B.
      
 0.792
MRPS27
Mitochondrial ribosomal protein S27.
      
 0.787
IFI27L2
Uncharacterized protein.
      
 0.705
PRICKLE3
Prickle planar cell polarity protein 3.
    
 
 0.687
CCDC85C
Coiled-coil domain containing 85C.
    
 
 0.668
STEAP3
STEAP3 metalloreductase.
      
 0.641
TCF20
Transcription factor 20.
   
  
 0.626
CDC42
Cell division cycle 42.
   
 0.609
COPS2
COP9 signalosome subunit 2.
      
 0.598
AZIN1
Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
      
 0.577
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.