STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF133Zinc finger protein 133. (667 aa)    
Predicted Functional Partners:
RBBP9
RB binding protein 9, serine hydrolase.
   
  
 0.876
SLC24A3
Solute carrier family 24 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.852
PIAS1
Protein inhibitor of activated STAT 1.
    
 
 0.789
MAP10
Microtubule associated protein 10.
      
 0.713
DZANK1
Double zinc ribbon and ankyrin repeat domains 1.
      
 0.667
ZNF282
Zinc finger protein 282.
   
  
0.654
SLC4A11
Solute carrier family 4 member 11.
   
  
 0.644
SEC22A
SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family.
    
 
 0.497
SLC27A2
Solute carrier family 27 member 2.
   
  
 0.483
ADCY5
Adenylate cyclase type 5; [Isoform 1]: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 
 0.475
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.