STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAFP00000061722ETS domain-containing protein. (407 aa)    
Predicted Functional Partners:
COP1
COP1 E3 ubiquitin ligase.
    
 
 0.585
DET1
DET1 partner of COP1 E3 ubiquitin ligase.
    
 
 0.533
STK40
Serine/threonine kinase 40.
    
   0.518
GFRA1
GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family.
      
 0.504
SPRY1
Sprouty RTK signaling antagonist 1.
      
 0.482
LPCAT1
Lysophosphatidylcholine acyltransferase 1.
      
 0.480
FOXA1
Forkhead box A1.
      
 0.475
NANOS2
Nanos C2HC-type zinc finger 2; Belongs to the nanos family.
      
 0.457
SPRY4
Sprouty RTK signaling antagonist 4.
      
 0.456
SOHLH1
Spermatogenesis and oogenesis specific basic helix-loop-helix 1.
      
 0.440
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.