STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIMK2LIM domain kinase 2. (838 aa)    
Predicted Functional Partners:
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 
 0.848
F1Q1C8_CANLF
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.835
CFL1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 
 0.834
CCDC154
Coiled-coil domain containing 154.
   
 
 0.725
SSH1
Slingshot protein phosphatase 1.
   
 
 0.650
SSH3
Slingshot protein phosphatase 3.
   
 
 0.635
DSTN
Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.
   
 
 0.629
J9NXU5_CANLF
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.628
ENSCAFP00000059814
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.628
ENSCAFP00000061155
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.628
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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