STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USO1USO1 vesicle transport factor. (974 aa)    
Predicted Functional Partners:
STX5
Syntaxin 5; Belongs to the syntaxin family.
   
 0.983
GOSR2
Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
    
 0.980
GOSR1
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
   
 0.977
BET1L
Bet1 golgi vesicular membrane trafficking protein like.
   
 0.973
GOLGB1
Golgin B1.
   
 
 0.951
BET1
Bet1 golgi vesicular membrane trafficking protein.
   
 0.939
RAB1A
Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...]
   
 0.894
F6XUK4_CANLF
Uncharacterized protein.
   
 0.890
SCFD1
Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.881
ENSCAFP00000043471
t-SNARE coiled-coil homology domain-containing protein.
    
 
 0.881
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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