STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAFP00000062604Uncharacterized protein. (133 aa)    
Predicted Functional Partners:
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).
    
 
 0.982
MYCN
BHLH domain-containing protein.
    
 
 0.881
MXD1
MAX dimerization protein 1.
    
 
 0.866
MXI1
MAX interactor 1, dimerization protein.
   
 
 0.826
MNT
MAX network transcriptional repressor.
    
 
 0.752
MYCL
MYCL proto-oncogene, bHLH transcription factor.
    
 
 0.695
MXD3
MAX dimerization protein 3.
    
 
 0.691
MGA
MAX dimerization protein MGA.
    
 
 0.677
L3MBTL2
L3MBTL histone methyl-lysine binding protein 2.
    
 
 0.616
MXD4
MAX dimerization protein 4.
    
 
 0.581
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]