STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNB3G2/mitotic-specific cyclin-B3; Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I (By similarity). (1352 aa)    
Predicted Functional Partners:
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.973
PLK1
Serine/threonine-protein kinase PLK.
   
 0.963
CCNB2
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 
0.937
CDC25A
Cell division cycle 25A.
   
 0.935
GADD45B
Growth arrest and DNA damage inducible beta.
    
 0.931
CCNB1
Uncharacterized protein; Belongs to the cyclin family.
   
 
0.924
SFN
Stratifin; Belongs to the 14-3-3 family.
    
 0.908
GADD45A
Growth arrest and DNA damage inducible alpha.
    
 0.901
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 
 0.885
CDC27
Cell division cycle 27.
   
 0.839
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.