node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AVL9 | DENND2D | ENSCAFP00000004693 | ENSCAFP00000053699 | AVL9 cell migration associated. | DENN domain containing 2D. | 0.446 |
AVL9 | EPDR1 | ENSCAFP00000004693 | ENSCAFP00000041729 | AVL9 cell migration associated. | Ependymin related 1. | 0.675 |
AVL9 | RAB11A | ENSCAFP00000004693 | ENSCAFP00000025408 | AVL9 cell migration associated. | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | 0.645 |
AVL9 | RASA3 | ENSCAFP00000004693 | ENSCAFP00000009695 | AVL9 cell migration associated. | RAS p21 protein activator 3. | 0.561 |
AVL9 | SCUBE2 | ENSCAFP00000004693 | ENSCAFP00000062725 | AVL9 cell migration associated. | DENN domain containing 5A. | 0.875 |
CHM | DENND2D | ENSCAFP00000048589 | ENSCAFP00000053699 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | DENN domain containing 2D. | 0.424 |
CHM | GDI1 | ENSCAFP00000048589 | ENSCAFP00000028963 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. | 0.460 |
CHM | GDI2 | ENSCAFP00000048589 | ENSCAFP00000007805 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | 0.460 |
CHM | RAB11A | ENSCAFP00000048589 | ENSCAFP00000025408 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | 0.620 |
CHM | RAB6A | ENSCAFP00000048589 | ENSCAFP00000038819 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | RAB6A, member RAS oncogene family. | 0.578 |
CHM | RAB6B | ENSCAFP00000048589 | ENSCAFP00000040398 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | RAB6B, member RAS oncogene family. | 0.575 |
CHM | SCUBE2 | ENSCAFP00000048589 | ENSCAFP00000062725 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | DENN domain containing 5A. | 0.410 |
DENND2D | AVL9 | ENSCAFP00000053699 | ENSCAFP00000004693 | DENN domain containing 2D. | AVL9 cell migration associated. | 0.446 |
DENND2D | CHM | ENSCAFP00000053699 | ENSCAFP00000048589 | DENN domain containing 2D. | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | 0.424 |
DENND2D | GDI1 | ENSCAFP00000053699 | ENSCAFP00000028963 | DENN domain containing 2D. | Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. | 0.406 |
DENND2D | GDI2 | ENSCAFP00000053699 | ENSCAFP00000007805 | DENN domain containing 2D. | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | 0.409 |
DENND2D | SCUBE2 | ENSCAFP00000053699 | ENSCAFP00000062725 | DENN domain containing 2D. | DENN domain containing 5A. | 0.444 |
EPDR1 | AVL9 | ENSCAFP00000041729 | ENSCAFP00000004693 | Ependymin related 1. | AVL9 cell migration associated. | 0.675 |
EPDR1 | SCUBE2 | ENSCAFP00000041729 | ENSCAFP00000062725 | Ependymin related 1. | DENN domain containing 5A. | 0.448 |
GDI1 | CHM | ENSCAFP00000028963 | ENSCAFP00000048589 | Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | 0.460 |