IGSF1 protein (Canis lupus familiaris) - STRING interaction network

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Score

IGSF1

Immunoglobulin superfamily member 1. (1340 aa)

Predicted Functional Partners:

ARHGAP36

0.640

CALCR

0.536

NFATC1

0.527

LOC483501

0.493

LOC483500

0.493

OR5AK2

0.493

DCSTAMP

0.491

CTSS

0.475

CTSK

0.475

FCER1G

0.468

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP36	IGSF1	ENSCAFP00000027712	ENSCAFP00000062790	Rho GTPase activating protein 36.	Immunoglobulin superfamily member 1.	0.640
ARHGAP36	OR5AK2	ENSCAFP00000027712	ENSCAFP00000052516	Rho GTPase activating protein 36.	Olfactory receptor.	0.872
CALCR	CTSK	ENSCAFP00000046092	ENSCAFP00000017808	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Cathepsin K; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.	0.712
CALCR	DCSTAMP	ENSCAFP00000046092	ENSCAFP00000000955	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Dendrocyte expressed seven transmembrane protein.	0.662
CALCR	IGSF1	ENSCAFP00000046092	ENSCAFP00000062790	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Immunoglobulin superfamily member 1.	0.536
CALCR	NFATC1	ENSCAFP00000046092	ENSCAFP00000031585	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Nuclear factor of activated T cells 1.	0.794
CTSK	CALCR	ENSCAFP00000017808	ENSCAFP00000046092	Cathepsin K; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	0.712
CTSK	CTSS	ENSCAFP00000017808	ENSCAFP00000017782	Cathepsin K; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.	Cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L (By similarity).	0.503
CTSK	DCSTAMP	ENSCAFP00000017808	ENSCAFP00000000955	Cathepsin K; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.	Dendrocyte expressed seven transmembrane protein.	0.691
CTSK	IGSF1	ENSCAFP00000017808	ENSCAFP00000062790	Cathepsin K; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.	Immunoglobulin superfamily member 1.	0.475
CTSK	NFATC1	ENSCAFP00000017808	ENSCAFP00000031585	Cathepsin K; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.	Nuclear factor of activated T cells 1.	0.812
CTSS	CTSK	ENSCAFP00000017782	ENSCAFP00000017808	Cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L (By similarity).	Cathepsin K; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.	0.503
CTSS	DCSTAMP	ENSCAFP00000017782	ENSCAFP00000000955	Cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L (By similarity).	Dendrocyte expressed seven transmembrane protein.	0.457
CTSS	IGSF1	ENSCAFP00000017782	ENSCAFP00000062790	Cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L (By similarity).	Immunoglobulin superfamily member 1.	0.475
DCSTAMP	CALCR	ENSCAFP00000000955	ENSCAFP00000046092	Dendrocyte expressed seven transmembrane protein.	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	0.662
DCSTAMP	CTSK	ENSCAFP00000000955	ENSCAFP00000017808	Dendrocyte expressed seven transmembrane protein.	Cathepsin K; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.	0.691
DCSTAMP	CTSS	ENSCAFP00000000955	ENSCAFP00000017782	Dendrocyte expressed seven transmembrane protein.	Cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L (By similarity).	0.457
DCSTAMP	IGSF1	ENSCAFP00000000955	ENSCAFP00000062790	Dendrocyte expressed seven transmembrane protein.	Immunoglobulin superfamily member 1.	0.491
DCSTAMP	NFATC1	ENSCAFP00000000955	ENSCAFP00000031585	Dendrocyte expressed seven transmembrane protein.	Nuclear factor of activated T cells 1.	0.800
FCER1G	IGSF1	ENSCAFP00000018972	ENSCAFP00000062790	Fc fragment of IgE receptor Ig.	Immunoglobulin superfamily member 1.	0.468