STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCP1Lymphocyte cytosolic protein 1. (753 aa)    
Predicted Functional Partners:
KLHL6
Kelch like family member 6.
   
 
 0.831
PPM1F
Protein phosphatase, Mg2+/Mn2+ dependent 1F.
   
  
 0.755
CAPZB
Capping actin protein of muscle Z-line subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.661
ARPC4
Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.
   
  
 0.642
LAPTM5
Lysosomal protein transmembrane 5.
   
    0.605
HCLS1
Hematopoietic cell-specific Lyn substrate 1.
   
 
 0.590
MGAM2
Maltase-glucoamylase 2 (putative).
    
 
 0.577
EFHD2
EF-hand domain family member D2.
      
 0.574
COLGALT2
Collagen beta(1-O)galactosyltransferase 2.
      
 0.570
BPIFB2
BPI fold containing family B member 2.
   
  
 0.568
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.