STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSL1NSL1 component of MIS12 kinetochore complex. (314 aa)    
Predicted Functional Partners:
DSN1
DSN1 component of MIS12 kinetochore complex.
   
 0.995
MIS12
Uncharacterized protein.
   
 0.964
SPC24
SPC24 component of NDC80 kinetochore complex.
   
 0.915
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.891
J9P4J4_CANLF
Uncharacterized protein.
   
 
 0.879
NDC80
NDC80 kinetochore complex component.
   
 0.858
ZWINT
ZW10 interacting kinetochore protein.
   
 
 0.844
SPC25
SPC25 component of NDC80 kinetochore complex.
   
 0.831
E2RJ84_CANLF
Uncharacterized protein.
    
 
 0.824
KNL1
Kinetochore scaffold 1.
   
 0.774
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.