STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSC22D3TSC22 domain family member 3. (249 aa)    
Predicted Functional Partners:
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.821
SGK1
Non-specific serine/threonine protein kinase.
   
 0.678
SGK3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.657
NCOA5
Nuclear receptor coactivator 5.
      
 0.590
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
   
 0.533
NRBP1
Nuclear receptor binding protein 1.
   
 
 0.524
FKBP5
Peptidylprolyl isomerase.
   
  
 0.516
WWP1
E3 ubiquitin-protein ligase.
   
 0.516
ZBTB8A
Zinc finger and BTB domain containing 8A.
    
 
 0.503
MAP3K6
Mitogen-activated protein kinase kinase kinase 6.
      
 0.489
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.