STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB14-2Uncharacterized protein. (225 aa)    
Predicted Functional Partners:
GRB14
Growth factor receptor bound protein 14.
 
      0.900
INSR
Tyrosine-protein kinase receptor.
    
 
 0.800
IGF1R
Tyrosine-protein kinase receptor.
    
 
 0.653
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
  
 0.584
GTF3A
General transcription factor IIIA.
    
 
 0.578
SREBF1
Sterol regulatory element binding transcription factor 1.
      
 0.574
TMEM160
Transmembrane protein 160.
      
 0.572
FAIM2
Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family.
      
 0.561
CRKL
CRK like proto-oncogene, adaptor protein.
    
 
 0.529
PERP
P53 apoptosis effector related to PMP22.
      
 0.525
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.