STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMOC2SPARC related modular calcium binding 2. (667 aa)    
Predicted Functional Partners:
OLFM4
Olfactomedin 4.
      
 0.765
BMP3
Bone morphogenetic protein 3; Belongs to the TGF-beta family.
      
 0.749
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.707
SSBP3
Single stranded DNA binding protein 3.
      
 0.659
MSI1
Musashi RNA binding protein 1.
   
  
 0.624
WDR27
WD repeat domain 27.
      
 0.607
CCDC3
Coiled-coil domain containing 3.
   
  
 0.601
ASCL2
Achaete-scute family bHLH transcription factor 2.
   
  
 0.598
PAX3
Paired box 3.
      
 0.587
THBS2
Thrombospondin 2.
   
  
 0.586
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.