STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EVA1AEva-1 homolog A, regulator of programmed cell death. (378 aa)    
Predicted Functional Partners:
AGBL5
ATP/GTP binding protein like 5.
      
 0.846
OSBPL6
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.781
GALNT13
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.684
GLIPR1
GLI pathogenesis related 1; Belongs to the CRISP family.
      
 0.674
ATG9A
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
      
 0.637
YTHDC1
YTH domain containing 1.
      
 0.636
ARPC1B
Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
      
 0.611
RPS6KB1
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
   
  
 0.584
ANKRD50
Ankyrin repeat domain 50.
      
 0.570
CFAP52
Cilia and flagella associated protein 52.
      
 0.566
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (28%) [HD]