STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGM3Transglutaminase 3. (856 aa)    
Predicted Functional Partners:
SALL4
Spalt like transcription factor 4.
      
 0.788
CDSN
Corneodesmosin.
   
  
 0.783
PDCD5
Programmed cell death 5.
      
 0.750
SEMA3B
Semaphorin 3B; Belongs to the semaphorin family.
      
 0.742
KCNMB1
Calcium-activated potassium channel subunit beta-1; Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca(2+)/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its prese [...]
   
  
 0.741
UVRAG
UV radiation resistance associated.
      
 0.731
CNFN
Cornifelin.
   
  
 0.729
SGK2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
      
 0.649
TCHH
Uncharacterized protein.
   
 
 0.630
NENF
Neudesin neurotrophic factor.
      
 0.593
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.