STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP8AP2Caspase 8 associated protein 2. (1974 aa)    
Predicted Functional Partners:
WDR76
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
   
  
 0.681
MYBPHL
Myosin binding protein H like.
      
 0.677
UBR7
Ubiquitin protein ligase E3 component n-recognin 7 (putative).
      
 0.636
DSCC1
DNA replication and sister chromatid cohesion 1.
   
  
 0.635
ATAD2
ATPase family AAA domain containing 2.
   
  
 0.618
GINS2
GINS complex subunit 2.
   
  
 0.618
PRIM1
Uncharacterized protein.
   
  
 0.600
CHAF1B
Chromatin assembly factor 1 subunit B.
   
  
 0.583
POLA1
DNA polymerase.
   
  
 0.577
G2E3
G2/M-phase specific E3 ubiquitin protein ligase.
   
  
 0.567
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.