STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHX35DEAH-box helicase 35. (701 aa)    
Predicted Functional Partners:
CDC40
Cell division cycle 40.
   
 0.952
CWC22
CWC22 spliceosome associated protein homolog.
   
 0.942
YJU2
YJU2 splicing factor homolog.
   
 0.928
SYF2
Uncharacterized protein.
    
 0.918
SRRM2
Serine/arginine repetitive matrix 2.
   
 0.913
DHX38
DEAH-box helicase 38.
  
0.911
MTREX
Mtr4 exosome RNA helicase.
   
 0.903
CWC25
CWC25 spliceosome associated protein homolog.
   
 0.898
PPIL1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.874
WDR70
WD repeat domain 70.
 
 
 0.865
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.