STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXL18F-box and leucine rich repeat protein 18. (756 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.899
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.854
RBX1
Ring-box 1.
    
 0.852
CAND1
Cullin associated and neddylation dissociated 1.
    
 0.670
NEDD8
NEDD8 ubiquitin like modifier.
   
 0.615
COMMD4
COMM domain containing 4.
   
 0.538
UBB
Ubiquitin B.
    
 0.537
COMMD8
COMM domain containing 8.
   
  0.535
RPS27A
Ubiquitin-like domain-containing protein.
    
  0.535
ENSCAFP00000050780
Ubiquitin-like domain-containing protein.
    
  0.535
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.